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There was a doseresponse association between the daily dose of metformin and a greater risk of neuropathy [49], which could suggest that low vitamin B12 concentrations are a direct cause of neuropathy in those patients

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Hydrogen also reduces the levels of inflammatory cytokines involved in inflammation and oxidative stress, and increased NFE2L2 (NRF2) expression results in reduced oxidative stress in both humans and animals [30,31,170,175]

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Your healthcare provider will conduct a comprehensive evaluation including medical history, physical examination, and relevant laboratory tests (such as renal and liver function, A1c/glucose, lipids, and pregnancy testing when applicable) to determine appropriateness for treatment

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Effects of axonal ion channel dysfunction on quality of life in type 2 diabetes

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